Amoxicillin
- Amoxicillin stops bacteria growth through the inhibition of cell wall synthesis
- Broad spectrum semisynthetic antibiotic used for the treatement of wide range of infections
- Covers a wide range against gram-positive bacteria like Staphylococcus aureus & Streptococcus pneumoniae with some added gram-negative bacteria also
- Achieves peak plasma level ( between 1 to 2 hours )
- Stable in the presence of Gastric Acid
- The safe & well tolerated antibiotic
Clavulanic acid
- Clavulanic acid is a β-lactamase inhibitor, overcomes Amoxicillin resistance in the bacteria that secrete β-lactamase enzyme
- Protects Amoxicillin from degradation by β-lactamase enzymes hence synergises spectrum
